Mechanism of Action

KO Studios produces illustrations and animations to explain the mechanisms of action of many different types of medications, treatments, medical conditions and pathogens; mechanisms which are often far too minute for the naked eye. Our expertise helps audiences to clearly understand the efficacy of a drug or the benefit of a treatment—information which is crucial when the drug is pending approval with the FDA or a company is seeking investors for their product.

Neuromyelitis Optica, KO Studios ©2011 All rights reserved

Neuromyelitis Optica

Journal of Neuromuscular Medicine

Neuromyelitis optica (NMO), also known as Devic's disease, is an autoimmune inflammatory disorder that causes swelling and inflammation of the optic nerves (optic neuritis) and the spinal cord (myelitis). It occurs when the immune system creates antibodies that react against the body's own cells in the central nervous system.

Award of Excellence
Association of Medical Illustrators


Verteporfin for Injection

Ciba Vision

Designed as a poster showing Macular Degeneration and MOA of drug. Verteporfin attaches to LDLs then travels to the vasculature within the eye, killing off proliferating vessels

Award of Excellence
Association of Medical Illustrators

Macular Degeneration, KO Studios © 2003 All Rights Reserved


Pulsed Radio-Frequency Therapy

AMP Orthopedics,
Whitespace Healthcare Marketing

PRF Therapy is designed to accomodate the patient, the physcician, and the biotech marketer. It illustrates the MOA of a PRF device in treating inflammation. It also is compared to NSAIDs and other narcotics used for similar conditions.

Award of Excellence, Rx Club

Click on image to view or watch on YouTube


Macular Degeneration and Angiogenesis

Macusight, Inc.

The images shown to the right are two from a large series of images on Macular Degeneration produced for a presentation created for Macusight, Inc.
Mechanisms of action occur at different cellular and molecular levels during the disease processes of Macular degeneration. Two of these are illustrated in the images shown here. VEGF promotes angiogenesis; a process that must be blocked for normal vascularization to take place. Poor vascularization leads to hypoxia; a condition that effects HIF-1a and leads to a multitude of transcriptional and cellular changes designed to promote angiogenesis and cellular proliferation..

KO Studios ©2007, All rights reserved